TMS for Treatment-Resistant Depression
TMS operates on the principle of electromagnetic induction, utilizing precisely targeted magnetic fields to stimulate neural activity in specific brain regions associated with depression. The procedure involves several key components and mechanisms:
- Magnetic Field Generation: High-intensity magnetic pulses are delivered through a specialized coil positioned against the scalp, creating focused electromagnetic fields that penetrate brain tissue.
- Targeted Brain Stimulation: The magnetic fields specifically target the left dorsolateral prefrontal cortex, a brain region known to be underactive in individuals with depression.
- Neuroplasticity Enhancement: Repeated stimulation promotes the formation of new neural connections and strengthens existing pathways involved in mood regulation and emotional processing.
- Non-invasive Precision: Unlike surgical interventions, TMS delivers therapeutic effects without requiring anesthesia, incisions, or systemic medication distribution.


How TMS Works for Treatment-Resistant Depression
The therapeutic mechanism of TMS addresses the underlying neurobiological factors that contribute to treatment-resistant depression through several interconnected processes.
Neurochemical Restoration
- Neurotransmitter Regulation: TMS stimulation increases the release of key neurotransmitters including serotonin, dopamine, and norepinephrine, which are often dysregulated in treatment-resistant depression.
- Synaptic Strengthening: Magnetic stimulation enhances synaptic plasticity, improving communication between neurons and restoring healthy brain connectivity patterns.
- Inflammatory Reduction: TMS treatment has been shown to reduce neuroinflammation, which plays a significant role in treatment-resistant depression and contributes to poor medication response.
Brain Network Optimization
- Default Mode Network Regulation: TMS helps normalize the default mode network, which is often hyperactive in depression and contributes to rumination and negative thought patterns.
- Connectivity Enhancement: The treatment improves connectivity between prefrontal regions and other brain areas involved in emotion regulation, executive function, and mood stability.
- Cortical Excitability Balance: TMS restores the balance between excitatory and inhibitory brain activity, addressing the neural dysfunction underlying treatment resistance.
Types of TMS Protocols for Treatment-Resistant Depression
- Traditional High-Frequency TMS: Delivers 10-20 Hz stimulation to the left dorsolateral prefrontal cortex, the most extensively studied and FDA-approved protocol for treatment-resistant depression.
- Low-Frequency TMS: Utilizes 1 Hz stimulation, typically applied to the right dorsolateral prefrontal cortex, effective for individuals who may not respond to high-frequency protocols.
- Theta Burst Stimulation (TBS): An accelerated form of TMS that delivers treatment in shorter sessions, providing rapid therapeutic effects with similar efficacy to traditional protocols.
- Deep TMS (dTMS): Uses specialized H-coil technology to stimulate deeper brain regions, reaching areas that traditional TMS cannot access and potentially benefiting complex treatment-resistant cases.
- Bilateral TMS: Combines stimulation of both left and right brain hemispheres in a single session, addressing the complex bilateral dysfunction often present in treatment-resistant depression.
- Personalized TMS: Utilizes neuroimaging and genetic testing to customize stimulation parameters based on individual brain anatomy and neurobiological profiles.

Our Core Treatments
Depression & Anxiety
Our new dTMS device will go deeper and cover more area than traditional TMS, providing better results.
TMS for OCD
We now have the only device approved by the FDA and covered by insurance for OCD.
TMS for Addictions
Smoking cessation has recently been approved by the FDA for our Brainsway device. Talk to us about your addictions.
How TMS Therapy Benefits GAD Treatment in Queen
TMS therapy provides several advantages for individuals dealing with Generalized Anxiety Disorder (GAD). This advanced, non-invasive treatment targets specific brain regions involved in mood and anxiety regulation, helping to alleviate symptoms effectively. Unlike medications, TMS does not come with common side effects such as drowsiness or weight gain, nor does it require hospitalization or anesthesia.
The benefits of TMS for GAD are significant. Many patients experience reduced anxiety levels, improved mood, and an increased ability to manage daily stress. By directly addressing the root causes of anxiety, TMS helps individuals find relief from persistent worry and regain control over their lives.
If you or someone you care about is struggling with Generalized Anxiety Disorder in Queens, LifeQuality TMS offers compassionate, state-of-the-art care to support your mental health journey. Ready to take the first step toward overcoming anxiety and enhancing your well-being? Contact us today to schedule a consultation and learn how TMS therapy can provide lasting relief for GAD.
Get In Touch With Us
info@lifequalitytms.com
(718) 400-0867
(718) 4000-TMS
26 Court St., Ste 808
Brooklyn, NY 11201