Anhedonia is a condition characterized by loss of interest and inability to experience joy from normally pleasurable activities. It manifests as persistent discontent, numbness, or emptiness instead of positive emotions. Anhedonia often results from neurotransmitter imbalances tied to mental health disorders like depression, PTSD, or schizophrenia. Addictions or certain medications can also contribute to pleasure loss.

Left unchecked, anhedonia takes a toll on one’s quality of life and health – disrupting appetites, motivation, relationships, and overall well-being. Though not yet formally classified as its own disorder, researchers increasingly recognize anhedonia as underpinning various mood disturbances. Fortunately recent therapies like TMS stimulation specifically target and treat neural circuitry governing positive emotions.